Fragmentation Through Polymerization (FTP): A new method to fragment DNA for next-generation sequencing
نویسندگان
چکیده
منابع مشابه
Non-random DNA fragmentation in next-generation sequencing
Next Generation Sequencing (NGS) technology is based on cutting DNA into small fragments, and their massive parallel sequencing. The multiple overlapping segments termed "reads" are assembled into a contiguous sequence. To reduce sequencing errors, every genome region should be sequenced several dozen times. This sequencing approach is based on the assumption that genomic DNA breaks are random ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2019
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0210374